{"product_id":"proteintech-22571-1-ap","title":"Proteintech, 22571-1-AP, SEMA6B Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe SEMA6B (22571-1-AP) by Proteintech is a Polyclonal antibody targeting SEMA6B in WB, IP, ELISA applications with reactivity to human, mouse samples\n22571-1-AP targets SEMA6B in WB, IP, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: MCF-7 cells, MDA-MB-231 cells,  mouse brain tissue\nPositive IP detected in: mouse brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSemaphorins (SEMAs) play critical roles in inflammation, angiogenesis, apoptosis, fibrosis, bone remodeling, and cell invasion. SEMA6B, the sixth member of the SEMA family, has shown significant correlations with the stage of liver fibrosis in hepatitis C virus-infected patients. SEMA6B is also involved in inflammatory responses and serves as a biomarker for macrophage-specific genes. Additionally, the level of SEMA6B in circulating monocytes has predictive value for cardiovascular disease. Also, SEMA6B can be a valuable biomarker for diagnosing HBV-ACLF12 (PMID: 39267780).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag16707 Product name: Recombinant human SEMA6B protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 625-888 aa of BC142617 Sequence: RERRELARRKDKEAILAHGAGEAVLSVSRLGERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDLDSGLLPTPEQTPLPQKRLPTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQPPAPGEPTPDGRLYAARPGRASHGDFPLTPHASPDRRRVVSAPTGPLDPASAADGLPRPWSPPPTGSLRRPLGPHAPPAATLRRTHTFNSGEARPGDRHRGCHARPGTDLAHLLPYGGADRTAPPVP Predict reactive species\nFull Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B\nCalculated Molecular Weight: 95, 74 kDa\nObserved Molecular Weight: 70 kDa\nGenBank Accession Number: BC142617\nGene Symbol: SEMA6B\nGene ID (NCBI): 10501\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen Affinity purified\nUNIPROT ID: Q9H3T3\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887796408489,"sku":"22571-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-22571-1-ap","provider":"Iright","version":"1.0","type":"link"}