{"product_id":"proteintech-22860-1-ap","title":"Proteintech, 22860-1-AP, ADAM33 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ADAM33 (22860-1-AP) by Proteintech is a Polyclonal antibody targeting ADAM33 in WB, ELISA applications with reactivity to human samples\n22860-1-AP targets ADAM33 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: MCF-7 cells, SK-BR-3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nADAM33 is a member of the 'a disintegrin and metalloprotease domain' family of proteins. Endogenous ADAM33 is detected in bronchus tissue, bronchial smooth muscle cells, and MRC-5 fibroblasts, consistent with a role in the pathophysiology of asthma(PMID:12535637).\nADAM33 is a novel tumour suppressor gene that may be useful as a molecular marker for invasive lobular carcinoma of the breast(PMID:19267929)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag18852 Product name: Recombinant human ADAM33 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 30-364 aa of BC125113 Sequence: VLQGHIPGQPVTPHWVLDGQPWRTVSLEEPVSKPDMGLVALEAEGQELLLELEKNHRLLAPGYIETHYGPDGQPVVLAPNHTDHCHYQGRVRGFPDSWVVLCTCSGMSGLITLSRNASYYLRPWPPRGSKDFSTHEIFRMEQLLTWKGTCGHRDPGNKAGMTSLPGGPQSRGRREARRTRKYLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLRTLDIQVALTGLEVWTERDRSRRQLRAFFRKGGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCGPGQECRDLCCFAHNCSLRPGAQCAHGDCCVRCLLKPAGALCRQAMGDCDL Predict reactive species\nFull Name: ADAM metallopeptidase domain 33\nCalculated Molecular Weight: 813 aa, 88 kDa\nObserved Molecular Weight: 70 kDa\nGenBank Accession Number: BC125113\nGene Symbol: ADAM33\nGene ID (NCBI): 80332\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9BZ11\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869802451113,"sku":"22860-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-22860-1-ap","provider":"Iright","version":"1.0","type":"link"}