{"product_id":"proteintech-23838-1-ap","title":"Proteintech, 23838-1-AP, ANXA2R Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ANXA2R (23838-1-AP) by Proteintech is a Polyclonal antibody targeting ANXA2R in IHC, ELISA applications with reactivity to human samples\n23838-1-AP targets ANXA2R in WB, IHC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: human prostate cancer tissue,  human brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:20-1:200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nANXA2R (annexin A2 receptor) is a receptor protein that interacts with annexin A2 (ANXA2). ANXA2R plays significant roles in various diseases. For instance, in renal cell carcinoma (RCC), high expression of ANXA2R is associated with poor prognosis. A recent study published in Nature revealed that SP140 regulates interferon mRNA stability and antiviral immunity by inhibiting a novel regulator, RESIST, which decreases the stability of Ifnb1 mRNA and thereby suppresses interferon expression. Notably, RESIST is the orthologue of human ANXA2R. This finding highlights the crucial role of ANXA2R in cellular signaling and immune responses.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag20807 Product name: Recombinant human C5orf39 protein Source: e coli. -derived, PET30a Tag: 6*His Domain: 1-193 aa of BC067873 Sequence: MEQHFLGCVKRAWDSAEVAPEPQPPPIVSSEDRGPWPLPLYPVLGEYSLDSCDLGLLSSPCWRLPGVYWQNGLSPGVQSTLEPSTAKPTEFSWPGTQKQQEAPVEEVGQAEEPDRLRLRQLPWSSPLHPWDRQQDTEVCDSGCLLERRHPPALQPWRHLPGFSDCLEWILRVGFAAFSVLWACCSRICGAKQP Predict reactive species\nFull Name: chromosome 5 open reading frame 39\nCalculated Molecular Weight: 193 aa, 22 kDa\nGenBank Accession Number: BC067873\nGene Symbol: ANXA2R\nGene ID (NCBI): 389289\nRRID: AB_2879333\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen Affinity purified\nUNIPROT ID: Q3ZCQ2\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869636645033,"sku":"23838-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-23838-1-ap","provider":"Iright","version":"1.0","type":"link"}