{"product_id":"proteintech-23913-1-ap","title":"Proteintech, 23913-1-AP, AES Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe AES (23913-1-AP) by Proteintech is a Polyclonal antibody targeting AES in WB, ELISA applications with reactivity to human, mouse, rat samples\n23913-1-AP targets AES in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: DU 145 cells, HEK-293 cells,  mouse skeletal muscle tissue,  rat skeletal muscle tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nAmino-terminal enhancer of split (AES), belongs to the groucho\/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members in order to forcefully repress the expression of other family member genes. AES can repress NFkB-regulated gene expression and is believed to have a significant role in initiating and maintaining cell differentiation events. AES has been found to suppress local invasion and intravasation through inhibition of the Notch pathway, leading to preventing the metastatic spread of endogenous tumors(PMID: 33754069).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag21021 Product name: Recombinant human AES protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-81 aa of BC113735 Sequence: MCHKNGFPQEGGITAAFLQKRKLRLSKNHRPARAKVTEHVRGTRPGRATAGPAASTRAAGSLFFDRWGNRGPAGCRGSSHL Predict reactive species\nFull Name: amino-terminal enhancer of split\nCalculated Molecular Weight: 264 aa, 29 kDa\nObserved Molecular Weight: 22-29 kDa\nGenBank Accession Number: BC113735\nGene Symbol: AES\nGene ID (NCBI): 166\nRRID: AB_3669425\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen Affinity purified\nUNIPROT ID: Q08117\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869804351657,"sku":"23913-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-23913-1-ap","provider":"Iright","version":"1.0","type":"link"}