{"product_id":"proteintech-24069-1-ap","title":"Proteintech, 24069-1-AP, ITIH4 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ITIH4 (24069-1-AP) by Proteintech is a Polyclonal antibody targeting ITIH4 in WB, IHC, ELISA applications with reactivity to human, mouse, rat samples\n24069-1-AP targets ITIH4 in WB, IHC, IF, IP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: human plasma, mouse lung tissue,  mouse serum,  rat serum\nPositive IHC detected in: human hepatocirrhosis tissue, human liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nITIH4(Inter-alpha-trypsin inhibitor heavy chain H4) is a liver-restricted plasma glycoprotein belonging to the serine protease inhibitor family, playing diverse roles in inflammation, extracellular matrix (ECM) stabilization, and cancer progression. Expressed mainly in hepatocytes, ITIH4 is secreted into the bloodstream, where it can be cleaved by plasma kallikrein into specific fragments. Functionally, ITIH4 acts as an anti-apoptotic and matrix-stabilizing molecule during liver development and regeneration, with its expression regulated by interleukin-6 (IL-6).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag21275 Product name: Recombinant human ITIH4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 622-932 aa of BC136393 Sequence: STFFKYYLQGAKIPKPEASFSPRRGWNRQAGAAGSRMNFRPGVLSSRQLGLPGPPDVPDHAAYHPFRRLAILPASATPATSNPDPAVSRVMNMKIEETTMTTQTPAPIQAPSAILPLPGQSVERLCVDPRHRQGPVNLLSDPEQGVEVTGQYEREKAGFSWIEVTFKNPLVWVHASPEHVVVTRNRRSSAYKWKETLFSVMPGLKMTMDKTGLLLLSDPDKVTIGLLFWDGRGEGLRLLLRDTDRFSSHVGGTLGQFYQEVLWGSPAASDDGRRTLRVQGNDHSATRERRLDYQEGPPGVEISCWSVEL Predict reactive species\nFull Name: inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)\nCalculated Molecular Weight: 103 kDa\nObserved Molecular Weight: 120 kDa\nGenBank Accession Number: BC136393\nGene Symbol: ITIH4\nGene ID (NCBI): 3700\nRRID: AB_2879426\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen Affinity purified\nUNIPROT ID: Q14624\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868942061737,"sku":"24069-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-24069-1-ap","provider":"Iright","version":"1.0","type":"link"}