{"product_id":"proteintech-24459-1-ap","title":"Proteintech, 24459-1-AP, C10orf67 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe C10orf67 (24459-1-AP) by Proteintech is a Polyclonal antibody targeting C10orf67 in WB, ELISA applications with reactivity to human samples\n24459-1-AP targets C10orf67 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: PC-3 cells,  A549 cells,  human testis tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:200-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nRNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is speciﬁcally expressed in testis. The RING ﬁnger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog\/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag21465 Product name: Recombinant human C10orf67 protein Source: e coli. -derived, PKG Tag: GST Domain: 1-184 aa of BC035732 Sequence: MALVRDRRAHYVMSIVIRWVHCFSSSLRGTFGTRWEAMKAKATELRVCCARRKREAREFKPPQMRGSTRLNISDDLKIGFFSTDHATQTDSSEILSVKELSSSTQKLAQMMKSLQVDFGFLKQLLQLKFEDRLKEESLSLFTILHDRILEIEKHYQQNEDKMRKSFNQQLADAIAVIKGMYQPL Predict reactive species\nFull Name: chromosome 10 open reading frame 67\nCalculated Molecular Weight: 184 aa, 21 kDa\nObserved Molecular Weight: 18-21 kDa\nGenBank Accession Number: BC035732\nGene Symbol: C10orf67\nGene ID (NCBI): 256815\nRRID: AB_2879558\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q8IYJ2\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46885359976617,"sku":"24459-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-24459-1-ap","provider":"Iright","version":"1.0","type":"link"}