{"product_id":"proteintech-24933-1-ap","title":"Proteintech, 24933-1-AP, KEPI Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe KEPI (24933-1-AP) by Proteintech is a Polyclonal antibody targeting KEPI in WB, ELISA applications with reactivity to human samples\n24933-1-AP targets KEPI in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293 cells, HeLa cells,  MDA-MB-231 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:3000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPPP1R14C, found as a morphine‐regulated brain gene, encodes protein phosphatase 1 regulatory inhibitor subunit 14C, and is identified as a potent inhibitor of PP1. Horvath and colleagues reported that PPP1R14C inhibited the release of neurotransmitters and promoted neuronal exocytosis by retaining synaptosome associated protein 25 (SNAP25) at a phosphorylated state.  Moreover, overexpression of PPP1R14C increased the phosphorylation of RB transcriptional co‐repressor 1 (RB1) to protect leukemic cells from chemotherapy.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag20645 Product name: Recombinant human KEPI protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-165 aa of BC015773 Sequence: MSVATGSSEAAGGASGGGARVFFQSPRGGAGGSPGSSSGSGSSREDSAPVATAAAAGQVQQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPEVEIDIDDLLDADSDEERASKLQEALVDCYKPTEEFIKELLSRIRGMRKLSPPQKKSV Predict reactive species\nFull Name: protein phosphatase 1, regulatory (inhibitor) subunit 14C\nCalculated Molecular Weight: 18 kDa\nObserved Molecular Weight: 20-22 kDa\nGenBank Accession Number: BC015773\nGene Symbol: PPP1R14C\nGene ID (NCBI): 81706\nRRID: AB_3085762\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q8TAE6\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887694106793,"sku":"24933-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-24933-1-ap","provider":"Iright","version":"1.0","type":"link"}