{"product_id":"proteintech-25029-1-ap","title":"Proteintech, 25029-1-AP, PAG1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PAG1 (25029-1-AP) by Proteintech is a Polyclonal antibody targeting PAG1 in WB, IHC, ELISA applications with reactivity to human, mouse samples\n25029-1-AP targets PAG1 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue\nPositive IHC detected in: human ovary cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPAG1, also named as CBP and PAG, promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. It is involved in cell adhesion signaling. PAG1 may play an important role in inhibiting the proliferation, invasion and metastasis of the cancer cells. PAG1 is a membrane protein with phosphor modification. The MW of PAG1 migrates to 50-65 kDa in WB detection.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag13393 Product name: Recombinant human PAG1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 82-432 aa of BC112159 Sequence: EQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESISDLQQGRDITRL Predict reactive species\nFull Name: phosphoprotein associated with glycosphingolipid microdomains 1\nCalculated Molecular Weight: 432 aa, 47 kDa\nObserved Molecular Weight: 50-60 kDa\nGenBank Accession Number: BC112159\nGene Symbol: PAG1\nGene ID (NCBI): 55824\nRRID: AB_2879858\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9NWQ8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887749681321,"sku":"25029-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-25029-1-ap","provider":"Iright","version":"1.0","type":"link"}