{"product_id":"proteintech-25265-1-ap","title":"Proteintech, 25265-1-AP, Nesprin 2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe Nesprin 2 (25265-1-AP) by Proteintech is a Polyclonal antibody targeting Nesprin 2 in WB, IF-P, ELISA applications with reactivity to human, mouse, rat samples\n25265-1-AP targets Nesprin 2 in WB, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293 cells\nPositive IF-P detected in: mouse brain tissue, rat brain tissue,  Human dorsal cerebral organoid\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\nImmunofluorescence (IF)-P: IF-P : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nNesprin-2 is a member of actin-binding proteins that localize to the outer nuclear membrane. As a nuclear envelope component it provides a link between cytoskeletal components of the cytoplasm and the nucleoplasm. Nesprin genes generate, through alternative splicing and alternative promoter and\/or terminator usage, a multitude of differentially expressed isoforms, differing in domain architecture and length. The largest protein isoform, known as NUANCE or GIANT, has a predicted MW around 796 kDa. Other isoforms range from 30 kDa to 119 kDa.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: spectrin repeat containing, nuclear envelope 2\nCalculated Molecular Weight: 799 kDa\nObserved Molecular Weight: 50-60 kDa\nGenBank Accession Number: NM_015180\nGene Symbol: Nesprin 2\nGene ID (NCBI): 23224\nRRID: AB_2879995\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q8WXH0\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869717909673,"sku":"25265-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-25265-1-ap","provider":"Iright","version":"1.0","type":"link"}