{"product_id":"proteintech-25690-1-ap","title":"Proteintech, 25690-1-AP, DPYD Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe DPYD (25690-1-AP) by Proteintech is a Polyclonal antibody targeting DPYD in WB, ELISA applications with reactivity to mouse samples\n25690-1-AP targets DPYD in WB, ELISA applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse liver tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag20885 Product name: Recombinant human DPYD protein Source: e coli. -derived, PET30a Tag: 6*His Domain: 1-173 aa of BC008379 Sequence: MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATETLILAFSLMNHL Predict reactive species\nFull Name: dihydropyrimidine dehydrogenase\nCalculated Molecular Weight: 1025 aa, 111 kDa\nObserved Molecular Weight: 111 kDa\nGenBank Accession Number: BC008379\nGene Symbol: DPYD\nGene ID (NCBI): 1806\nRRID: AB_3085814\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q12882\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887313473705,"sku":"25690-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-25690-1-ap","provider":"Iright","version":"1.0","type":"link"}