{"product_id":"proteintech-28307-1-ap","title":"Proteintech, 28307-1-AP, RBM48 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe RBM48 (28307-1-AP) by Proteintech is a Polyclonal antibody targeting RBM48 in WB, IF\/ICC, ELISA applications with reactivity to human, mouse samples\n28307-1-AP targets RBM48 in WB, IF\/ICC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue, mouse testis tissue\nPositive IF\/ICC detected in: A431 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nRBM48 (RNA Binding Motif Protein 48) is a gene encoding an RNA-binding protein, belonging to the RNA-binding motif protein family, which plays an important role in the splicing process of U12-type introns. Deletion of RBM48 leads to an increase in the retention of U12-type introns, which affects cell differentiation and proliferation. And mutations in RBM48 are associated with a variety of diseases. For example, U12 intron splicing defects are associated with myelodysplastic syndromes (MDS) and may increase the risk of acute myeloid leukemia (AML). RBM48 may serve as a prognostic marker in certain cancers, such as renal smoky cell carcinoma, renal clear cell carcinoma, and hepatocellular carcinoma.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag27277 Product name: Recombinant human C7orf64 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 68-367 aa of BC104865 Sequence: LYGAIEQYNALDEYPAEDFTEVYLIKFMNLQSARTAKRKMDEQSFFGGLLHVCYAPEFETVEETRKKLQMRKAYVVKTTENKDHYVTKKKLVTEHKDTEDFRQDFHSEMSGFCKAALNTSAGNSNPYLPYSCELPLCYFSSKCMCSSGGPVDRAPDSSKDGRNHHKTMGHYNHNDSLRKTQINSLKNSVACPGAQKAITSSEAVDRFMPRTTQLQERKRRREDDRKLGTFLQTNPTGNEIMIGPLLPDISKVDMHDDSLNTTANLIRHKLKEVISSVPKPPEDKPEDVHTSHPLKQRRRI Predict reactive species\nFull Name: chromosome 7 open reading frame 64\nObserved Molecular Weight: 40 kDa\nGenBank Accession Number: BC104865\nGene Symbol: C7orf64\nGene ID (NCBI): 84060\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q5RL73\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887780516009,"sku":"28307-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-28307-1-ap","provider":"Iright","version":"1.0","type":"link"}