{"product_id":"proteintech-28676-1-ap","title":"Proteintech, 28676-1-AP, VPS13C Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe VPS13C (28676-1-AP) by Proteintech is a Polyclonal antibody targeting VPS13C in WB, IHC, ELISA applications with reactivity to human, mouse, rat samples\n28676-1-AP targets VPS13C in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, mouse brain tissue,  rat brain tissue\nPositive IHC detected in: human stomach tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:12000\nImmunohistochemistry (IHC): IHC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nVPS13 (vacuolar protein sorting 13) acts at membrane contact sites between intracellular organelles to transport lipids.  There are four VPS13 family members in human - VPS13A, VPS13B, VPS13C and VPS13D. Mutations in human VPS13 genes are linked to rare neurodegenerative disorders: chorea- acanthocytosis (VPS13A), Cohen syndrome (VPS13B), predispose to early onset into Parkinson's disease (VPS13C) and lead to ataxia\/spastic paraplegia (VPS13D) (PMID: 30656912).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag29434 Product name: Recombinant mouse VPS13C protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 3575-3699 aa of NM_177184 Sequence: GIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLENHIKKLEGEAYQFHCAVPGNKRAVLMITNRRALFIKEVEILGHMSVDWQCLFEDFVCPPEVSENLLKISVKEQGLFHKKDSAN Predict reactive species\nFull Name: vacuolar protein sorting 13C (yeast)\nObserved Molecular Weight: 422 kDa\nGenBank Accession Number: NM_177184\nGene Symbol: Vps13c\nGene ID (NCBI): 320528\nRRID: AB_2881191\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q8BX70\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868975517865,"sku":"28676-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-28676-1-ap","provider":"Iright","version":"1.0","type":"link"}