{"product_id":"proteintech-28847-1-ap","title":"Proteintech, 28847-1-AP, Phospho-ASK1 (Ser83) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-ASK1 (Ser83) (28847-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-ASK1 (Ser83) in WB, ELISA applications with reactivity to Human samples\n28847-1-AP targets Phospho-ASK1 (Ser83) in WB, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293T cells, λ phosphatase treated HEK-293T cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily.  ASK1 is reportedly regulated by phosphorylation and dephosphorylation at four different phosphorylation sites.    ASK1 activation is accompanied by phosphorylation of Thr845 and dephosphorylation of Ser83, Ser967, and Ser1034.    STRAP actually decreased Thr838 (corresponding to Thr845 in mice) phosphorylation but increased Ser83 and Ser967 phosphorylation, an effect that would inactivate ASK1. (PMID: 19880523)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: mitogen-activated protein kinase kinase kinase 5\nCalculated Molecular Weight: 155 kDa\nObserved Molecular Weight: 150 kDa\nGenBank Accession Number: BC054503\nGene Symbol: ASK1\nGene ID (NCBI): 4217\nRRID: AB_3085337\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q99683\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887759020201,"sku":"28847-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-28847-1-ap","provider":"Iright","version":"1.0","type":"link"}