{"product_id":"proteintech-28925-1-ap","title":"Proteintech, 28925-1-AP, Phospho-PLA2G4A (Ser505) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-PLA2G4A (Ser505) (28925-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-PLA2G4A (Ser505) in WB, IF\/ICC, ELISA applications with reactivity to Human samples\n28925-1-AP targets Phospho-PLA2G4A (Ser505) in WB, IF\/ICC, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: λ phosphatase treated HeLa cells\nPositive IF\/ICC detected in: λ phosphatase treated HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPLA2G4A, also named as cPLA2 (cytosolic phospholipase A2), is a highly conserved and widely expressed enzyme which can promote lipid mediator production. PLA2G4A plays a major role in membrane lipid remodeling and biosynthesis of lipid mediators of the inflammatory response. It has been reported that the activity and expression levels of PLA2G4A are upregulated in several neurodegenerative diseases. PLA2G4A can be activated at the phosphorylation site of ser505 by MAP kinase. (PMID: 25838312, 8381049, 31238788)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: phospholipase A2, group IVA (cytosolic, calcium-dependent)\nCalculated Molecular Weight: 749 aa, 85 kDa\nObserved Molecular Weight: 100-110 kDa\nGenBank Accession Number: BC114340\nGene Symbol: PLA2G4A\nGene ID (NCBI): 5321\nRRID: AB_2918213\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P47712\nStorage Buffer: PBS with 0.02% sodium azide, 50% glycerol, and 0.05% BSA, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869484273833,"sku":"28925-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-28925-1-ap","provider":"Iright","version":"1.0","type":"link"}