{"product_id":"proteintech-29375-1-ap","title":"Proteintech, 29375-1-AP, IDS Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe IDS (29375-1-AP) by Proteintech is a Polyclonal antibody targeting IDS in WB, ELISA applications with reactivity to Human, mouse, rat samples\n29375-1-AP targets IDS in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue, rat brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag31132 Product name: Recombinant human IDS protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 160-312 aa of BC006170 Sequence: PSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQREDVQALNISVPYGPIPVDFQEDQSSTGFRLKTSSTRKYK Predict reactive species\nFull Name: iduronate 2-sulfatase\nCalculated Molecular Weight: 312aa,35 kDa; 550aa,62 kDa\nObserved Molecular Weight: 65-72 kDa\nGenBank Accession Number: BC006170\nGene Symbol: IDS\nGene ID (NCBI): 3423\nRRID: AB_3669687\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P22304\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887675723945,"sku":"29375-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-29375-1-ap","provider":"Iright","version":"1.0","type":"link"}