{"product_id":"proteintech-29946-1-ap","title":"Proteintech, 29946-1-AP, MYD88 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe MYD88 (29946-1-AP) by Proteintech is a Polyclonal antibody targeting MYD88 in WB, IHC, ELISA applications with reactivity to mouse, rat samples\n29946-1-AP targets MYD88 in WB, IHC, IF, ELISA applications and shows reactivity with mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: NR8383 cells, RAW 264.7 cells,  mouse liver tissue,  rat liver tissue\nPositive IHC detected in: mouse liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:3000\nImmunohistochemistry (IHC): IHC : 1:400-1:1600\n\u003cb\u003eBackground Information\u003c\/b\u003e\nMYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the interleukin-1 receptor (IL-1R) and most Toll-like receptors (TLRs), which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis. MYD88 is detected in bone marrow.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse, rat\nCited Reactivity: mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag30662 Product name: Recombinant mouse MYD88 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 50-150 aa of NM_010851 Sequence: LAEEMGFEYLEIRELETRPDPTRSLLDAWQGRSGASVGRLLELLALLDREDILKELKSRIEEDCQKYLGKQQNQESEKPLQVARVESSVPQTKELGGITTL Predict reactive species\nFull Name: myeloid differentiation primary response gene 88\nCalculated Molecular Weight: 34 kDa\nObserved Molecular Weight: 29-34 kDa\nGenBank Accession Number: NM_010851\nGene Symbol: Myd88\nGene ID (NCBI): 17874\nRRID: AB_3076471\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P22366\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869005205673,"sku":"29946-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-29946-1-ap","provider":"Iright","version":"1.0","type":"link"}