{"product_id":"proteintech-30449-1-ap","title":"Proteintech, 30449-1-AP, CD25\/IL-2RA Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CD25\/IL-2RA (30449-1-AP) by Proteintech is a Polyclonal antibody targeting CD25\/IL-2RA in WB, ELISA applications with reactivity to human samples\n30449-1-AP targets CD25\/IL-2RA in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: MJ cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nProliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor following T lymphocyte activation. The receptor for IL-2 has three forms, generated by different combinations of three different proteins, the alpha chain (IL-2R alpha), the beta chain (IL-2R beta), and the gamma chain (IL-2R gamma) (PMID: 8476561). IL-2R alpha (also known as CD25) is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. CD25 is also found on natural CD4+ Foxp3+ Treg cells (PMID: 22585674).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Recombinant protein Predict reactive species\nFull Name: interleukin 2 receptor, alpha\nCalculated Molecular Weight: 272 aa, 31 kDa\nObserved Molecular Weight: 55-65 kDa\nGenBank Accession Number: BC156627\nGene Symbol: IL2RA\nGene ID (NCBI): 3559\nRRID: AB_3669723\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P01589\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46886160662697,"sku":"30449-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-30449-1-ap","provider":"Iright","version":"1.0","type":"link"}