{"product_id":"proteintech-30692-1-ap","title":"Proteintech, 30692-1-AP, IQGAP2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe IQGAP2 (30692-1-AP) by Proteintech is a Polyclonal antibody targeting IQGAP2 in WB, IHC, ELISA applications with reactivity to human, mouse samples\n30692-1-AP targets IQGAP2 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HepG2 cells, HuH-7 cells,  Ramos cells,  human peripheral blood platelets,  mouse testis tissue\nPositive IHC detected in: human stomach tissue, human intrahepatic cholangiocarcinoma tissue,  mouse stomach tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIQGAP2, a member of the IQGAP family, functions as a tumor suppressor in most of the cancers. IQGAP2 contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. IQGAP2 interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag33518 Product name: Recombinant human IQGAP2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 519-727 aa of NM_006633 Sequence: DEIQQAVDDANVDKDRAKQWVTLVVDVNQCLEGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSWLKLNLHKKYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSASEELLLRFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDNTDSIVKI Predict reactive species\nFull Name: IQ motif containing GTPase activating protein 2\nCalculated Molecular Weight: 181 kDa\nObserved Molecular Weight: 181 kDa\nGenBank Accession Number: NM_006633\nGene Symbol: IQGAP2\nGene ID (NCBI): 10788\nRRID: AB_3086388\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q13576\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887686209705,"sku":"30692-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-30692-1-ap","provider":"Iright","version":"1.0","type":"link"}