{"product_id":"proteintech-30696-1-ap","title":"Proteintech, 30696-1-AP, DFNA5\/GSDME Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe DFNA5\/GSDME (30696-1-AP) by Proteintech is a Polyclonal antibody targeting DFNA5\/GSDME in WB, ELISA applications with reactivity to mouse, rat samples\n30696-1-AP targets DFNA5\/GSDME in WB, ELISA applications and shows reactivity with mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Neuro-2a cells, J774A.1 cells,  mouse brain tissue,  rat brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDFNA5 (deafness, autosomal dominant 5), also known as GSDME or ICERE-1, is a 496 amino acid protein that is expressed in cochlea tissue, as well as in placenta, brain, heart, liver, lung and pancreas. Defects in the gene encoding DFNA5 are the cause of non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of sensorineural hearing loss that results from damage to one of various structures that receive sound information in the brain. 30696-1-AP can detect full-length GSDME and cleaved GSDME.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag33622 Product name: Recombinant mouse Dfna5 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-200 aa of BC132303 Sequence: MFAKATRNFLKEVDAGGDLISVSHLNDSDKLQLLSLVTKKKRYWCWQRPKYQILSATLEDVLTEGHCLSPVVVESDFVKYESKCENHKSGAIGTVVGKVKLNVGGKGVVESHSSFGTLRKQEVDVQQLIQDAVKRTVNMDNLVLQQVLESRNEVLCVLTQKIMTTQKCVISEHVQSEETCGGMVGIQTKTIQVSATEDGT* Predict reactive species\nFull Name: deafness, autosomal dominant 5 (human)\nCalculated Molecular Weight: 57 kDa\nObserved Molecular Weight: 57 kDa, 35 kDa\nGenBank Accession Number: BC132303\nGene Symbol: DFNA5\/GSDME\nGene ID (NCBI): 54722\nRRID: AB_3669751\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9Z2D3\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868838023337,"sku":"30696-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-30696-1-ap","provider":"Iright","version":"1.0","type":"link"}