{"product_id":"proteintech-30937-1-ap","title":"Proteintech, 30937-1-AP, Phospho-Cardiac Troponin I (Ser23\/24) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-Cardiac Troponin I (Ser23\/24) (30937-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-Cardiac Troponin I (Ser23\/24) in WB, ELISA applications with reactivity to Human, mouse samples\n30937-1-AP targets Phospho-Cardiac Troponin I (Ser23\/24) in WB, ELISA applications and shows reactivity with Human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse heart tissue, λ phosphatase treated mouse heart tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCardiac Troponin I (cTnI) is produced by cardiac muscle. To date, most investigative effort in phosphorylation mediated regulation of cTnI function has focused on the actions of PKA and PKC. Evidence from studies in a variety of systems, ranging from reconstituted myofilament proteins to cultured myocytes or transgenic animals with heterologous expression of modified cTnI proteins, indicates that PKA-mediated functional effects (eg, decreased myofilament Ca2 sensitivity) are mediated principally through the phosphorylation of Ser22\/23 (equivalent to Ser23\/24, including the initiating Met, in the rodent sequence) within the unique N-terminal extension of cTnI. (PMID: 15514163)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: troponin I type 3 (cardiac)\nCalculated Molecular Weight: 210 aa, 24 kDa\nObserved Molecular Weight: 26 kDa\nGenBank Accession Number: BC096165\nGene Symbol: Cardiac Troponin I\nGene ID (NCBI): 7137\nRRID: AB_3669787\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P19429\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887759118505,"sku":"30937-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-30937-1-ap","provider":"Iright","version":"1.0","type":"link"}