{"product_id":"proteintech-31215-1-ap","title":"Proteintech, 31215-1-AP, PTPN12 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PTPN12 (31215-1-AP) by Proteintech is a Polyclonal antibody targeting PTPN12 in WB, IF\/ICC, ELISA applications with reactivity to human samples\n31215-1-AP targets PTPN12 in WB, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293T cells, HeLa cells,  HepG2 cells,  MCF-7 cells\nPositive IF\/ICC detected in: A431 cells, U-251 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPTPN12 (Tyrosine-protein phosphatase non-receptor type 12), also referred to as PTP-PEST (PTP-proline, glutamic acid, serine, and threonine-rich), is a cytoplasmic PTP expressed in a wide spectrum of cell types. PTPN12 has been identified as a potent tumor suppressor in human cancers and a critical regulator of cell adhesion and migration (PMID: 26391955, 29743287). PTPN12 is phosphorylated on serine and threonine residues and is rich in proline (P), glutamate (E), serine (S), and threonine (T) residues. Western blot analysis detected PTPN12 at an apparent molecular mass of 110 kDa.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag35382 Product name: Recombinant human PTPN12 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 603-780 aa of NM_002835.3 Sequence: SDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT Predict reactive species\nFull Name: protein tyrosine phosphatase, non-receptor type 12\nCalculated Molecular Weight: 88kDa\nObserved Molecular Weight: 110-125 kDa\nGenBank Accession Number: NM_002835.3\nGene Symbol: PTPN12\nGene ID (NCBI): 5782\nRRID: AB_3669905\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q05209\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887776878761,"sku":"31215-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-31215-1-ap","provider":"Iright","version":"1.0","type":"link"}