{"product_id":"proteintech-31446-1-ap","title":"Proteintech, 31446-1-AP, CD40 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CD40 (31446-1-AP) by Proteintech is a Polyclonal antibody targeting CD40 in WB, ELISA applications with reactivity to mouse samples\n31446-1-AP targets CD40 in WB, ELISA applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: J774A.1 cells, RAW 264.7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD40, also known as TNFRSF5 or Bp50, is a member of the tumor necrosis factor (TNF) receptor (TNFR) family. It is expressed on a wide range of cell types including B cells, macrophages, and dendritic cells (PMID: 19426221). CD40 acts as a receptor for TNFSF5\/CD40LG, which is expressed on activated T cells. This interaction is essential for B cell proliferation, expression of activation markers, immunoglobulin production, and isotype switching (PMID: 8809473). This interaction is also crucial for the formation of memory B cells and germinal centers, and signaling through CD40 prevents apoptosis of germinal center B cells.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Recombinant protein Predict reactive species\nFull Name: CD40 antigen\nCalculated Molecular Weight: 32 kDa\nObserved Molecular Weight: 38 kDa\nGenBank Accession Number: NM_011611.2\nGene Symbol: Cd40\nGene ID (NCBI): 21939\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: P27512-1\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46886255886505,"sku":"31446-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-31446-1-ap","provider":"Iright","version":"1.0","type":"link"}