{"product_id":"proteintech-32204-1-ap","title":"Proteintech, 32204-1-AP, DNAJC5 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe DNAJC5 (32204-1-AP) by Proteintech is a Polyclonal antibody targeting DNAJC5 in WB, IHC, IF\/ICC, ELISA applications with reactivity to human, mouse, rat samples\n32204-1-AP targets DNAJC5 in WB, IHC, IF\/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, mouse brain tissue,  rat brain tissue\nPositive IHC detected in: human placenta tissue, mouse cerebellum tissue,  mouse lung tissue,  mouse pancreas tissue,  rat liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunohistochemistry (IHC): IHC : 1:250-1:1000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDNAJC5 (DnaJ homolog subfamily C member 5), also known as cysteine string protein α (CSPα), is a member of the HSP40 (DNAJ) family of proteins, as well as a co-chaperone of HSC70, and has been shown to control the extracellular release of many neurodegenerative disease proteins. DNAJC5 contains three structural domains - -a common N-terminal J structural domain conserved in DNAJ proteins, the cysteine string (CS) central structural domain, which is highly palmitoylated and anchors the protein to late endosomes, and an overall disordered C-terminal structural domain. Mutations in DNAJC5 have been strongly implicated in the development of human diseases such as neuronal waxy lipofuscinosis, cystic fibrosis, Huntington's disease and Parkinson's disease.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag35443 Product name: Recombinant human DNAJC5 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 110-198 aa of NM_025219.2 Sequence: FVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN Predict reactive species\nFull Name: DnaJ (Hsp40) homolog, subfamily C, member 5\nCalculated Molecular Weight: 22kDa，198aa\nObserved Molecular Weight: 30 kDa\nGenBank Accession Number: NM_025219.2\nGene Symbol: DNAJC5\nGene ID (NCBI): 80331\nRRID: AB_3670222\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q9H3Z4\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887257538729,"sku":"32204-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-32204-1-ap","provider":"Iright","version":"1.0","type":"link"}