{"product_id":"proteintech-32848-1-ap","title":"Proteintech, 32848-1-AP, PAK3 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PAK3 (32848-1-AP) by Proteintech is a Polyclonal antibody targeting PAK3 in WB, ELISA applications with reactivity to human, mouse, rat, pig samples\n32848-1-AP targets PAK3 in WB, ELISA applications and shows reactivity with human, mouse, rat, pig samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: fetal human brain tissue, mouse brain tissue,  pig brain tissue,  rat brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPAK3, also known as p21-activated kinase 3, is a member of the PAK family of serine\/threonine protein kinases, classified as Group I PAK kinases along with PAK1 and PAK2. PAK3 is predominantly expressed in neural cells, especially in regions such as the brain. PAK3 plays a crucial role in dendritic spine development and synaptic plasticity. PAK3 plays an important role in cell migration and morphology. It regulates dynamic changes in the actomyosin cytoskeleton, microtubules, and adhesion interactions with the microenvironment. In neurons and other cell types, PAK3 contributes to cell migration, neurite growth, and dendritic spine morphogenesis by participating in signaling cascades that control cell adhesion and cell motility. Mutations in PAK3 are associated with X-linked non-syndromic intellectual disability.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat, pig\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag38566 Product name: Recombinant human PAK3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-55 aa of NM_001128173.2 Sequence: MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGG Predict reactive species\nFull Name: p21 protein (Cdc42\/Rac)-activated kinase 3\nCalculated Molecular Weight: 62kDa，559aa\nObserved Molecular Weight: 64 kDa\nGenBank Accession Number: NM_001128173.2\nGene Symbol: PAK3\nGene ID (NCBI): 5063\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: O75914\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887749877929,"sku":"32848-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-32848-1-ap","provider":"Iright","version":"1.0","type":"link"}