{"product_id":"proteintech-32953-1-ap","title":"Proteintech, 32953-1-AP, PANK4 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PANK4 (32953-1-AP) by Proteintech is a Polyclonal antibody targeting PANK4 in WB, ELISA applications with reactivity to human, mouse, rat samples\n32953-1-AP targets PANK4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293 cells, HeLa cells,  mouse skeletal muscle tissue,  rat skeletal muscle tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:3000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPANK4 (Pantothenate Kinase 4) is a member of the pantothenate kinase family, which is involved in the biosynthesis of coenzyme A (CoA). However, unlike other members of the family, PANK4 lacks the residues required for kinase activity and instead contains a phosphatase domain (DUF89) that can dephosphorylate 4'-phosphopantetheine, an intermediate in CoA biosynthesis (PMID: 30927326). This suggests that PANK4 may act as a pseudoenzyme, regulating cellular CoA levels by antagonizing CoA production (PMID: 39746949).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag38232 Product name: Recombinant human PANK4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-178 aa of NM_018216.2 Sequence: MAECGASGSGSSGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLVNTETKVIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFR Predict reactive species\nFull Name: pantothenate kinase 4\nCalculated Molecular Weight: 86 kDa，773aa\nObserved Molecular Weight: 86 kDa\nGenBank Accession Number: NM_018216.2\nGene Symbol: PANK4\nGene ID (NCBI): 55229\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q9NVE7\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887750369449,"sku":"32953-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-32953-1-ap","provider":"Iright","version":"1.0","type":"link"}