{"product_id":"proteintech-33459-1-ap","title":"Proteintech, 33459-1-AP, IQCG Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe IQCG (33459-1-AP) by Proteintech is a Polyclonal antibody targeting IQCG in WB, ELISA applications with reactivity to human, mouse samples\n33459-1-AP targets IQCG in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse testis tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nHuman IQ motif containing G (IQCG) gene was first reported to be involved in the chromosome translocation in a case of acute T-lymphoid\/myeloid leukemia. The expression of Iqcg is prominently enriched in the testis of mice and reveals an ordered expression pattern during spermatogenesis. Iqcg knockout (KO) mice are sterile, due to the severe malformation and total immobility of their spermatozoa.  The axoneme in the KO sperm flagellum is disorganized and hardly any typical normal \"9+2\" pattern, composed of two central microtubules surrounded by nine microtubular doublets, could be found in the KO spermatids. However, the cilia structures in the trachea and oviduct, as well as histological appearances of other major tissues, remain unaffected in the KO mice, suggesting Iqcg's specific role in spermiogenesis (PMID: 24849454).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag37506 Product name: Recombinant human IQCG protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-372 aa of BC004816 Sequence: TDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLDKLPMDSTITKIPSPLITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSHVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPKDKVDSKDSKGKGKGKDKRRGKKK Predict reactive species\nFull Name: IQ motif containing G\nCalculated Molecular Weight: 51 kDa\nObserved Molecular Weight: 50 kDa\nGenBank Accession Number: BC004816\nGene Symbol: IQCG\nGene ID (NCBI): 84223\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q9H095\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887686144169,"sku":"33459-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-33459-1-ap","provider":"Iright","version":"1.0","type":"link"}