{"product_id":"proteintech-55191-1-ap","title":"Proteintech, 55191-1-AP, EWS Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe EWS (55191-1-AP) by Proteintech is a Polyclonal antibody targeting EWS in WB, IHC, ELISA applications with reactivity to human, mouse, rat samples\n55191-1-AP targets EWS in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: K-562 cells, mouse testis tissue,  Jurkat cells\nPositive IHC detected in: human colon cancer tissue,  human small intestine tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nEWS, also named as WSR1, belongs to the RRM TET family. It might normally function as a repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. This antibody is specific to EWS.\nAnd a 90 kDa band also could be detected (PMID:23552423).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: Ewing sarcoma breakpoint region 1\nCalculated Molecular Weight: 68 kDa\nObserved Molecular Weight: 68-70 kDa\nGenBank Accession Number: NM_005243\nGene Symbol: EWS\nGene ID (NCBI): 2130\nRRID: AB_10860907\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q01844\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868980236457,"sku":"55191-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-55191-1-ap","provider":"Iright","version":"1.0","type":"link"}