{"product_id":"proteintech-55227-1-ap","title":"Proteintech, 55227-1-AP, SPTA1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe SPTA1 (55227-1-AP) by Proteintech is a Polyclonal antibody targeting SPTA1 in WB, IF-P, FC (Intra), ELISA applications with reactivity to human, rat samples\n55227-1-AP targets SPTA1 in WB, IF-P, FC (Intra), ELISA applications and shows reactivity with human, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: rat red blood cells, human blood\nPositive IF-P detected in: mouse lung tissue\nPositive FC (Intra) detected in: K-562 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:200-1:1000\nImmunofluorescence (IF)-P: IF-P : 1:50-1:500\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nAlpha 1 Spectrin also known as SPTA1, EL2, belongs to the spectrin family. Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Mutations in SPTA1 result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3(PMID: 1541680, 8941647).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: spectrin, alpha, erythrocytic 1 (elliptocytosis 2)\nCalculated Molecular Weight: 280 kDa\nObserved Molecular Weight: 280 kDa\nGenBank Accession Number: NM_003126\nGene Symbol: SPTA1\nGene ID (NCBI): 6708\nRRID: AB_3086436\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P02549\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887815774377,"sku":"55227-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-55227-1-ap","provider":"Iright","version":"1.0","type":"link"}