{"product_id":"proteintech-55326-1-ap","title":"Proteintech, 55326-1-AP, QSER1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe QSER1 (55326-1-AP) by Proteintech is a Polyclonal antibody targeting QSER1 in IHC, IF\/ICC, ELISA applications with reactivity to human samples\n55326-1-AP targets QSER1 in IHC, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: human pancreas cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nQSER1, a recently characterized protein, whose activity has been tightly associated with the protection of DNA methylation sites in hESCs. QSER1 is widely up-regulated in multiple cancers, and its up-regulation correlates with poor clinic outcomes (PMID: 36371602). QSER1 depletion leads to NODAL de-repression and associates with increased RNA Polymerase II occupancy at YAP1bound enhancers, pointing to a QSER1 contribution maintaining low transcriptional activity on certain genomic regions (PMID: 33833093, 35210841).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: glutamine and serine rich 1\nCalculated Molecular Weight: 190 kDa\nGenBank Accession Number: NM_001076786\nGene Symbol: QSER1\nGene ID (NCBI): 79832\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q2KHR3\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887778025641,"sku":"55326-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-55326-1-ap","provider":"Iright","version":"1.0","type":"link"}