{"product_id":"proteintech-60402-8-ig","title":"Proteintech, 60402-8-Ig, MYO5B Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe MYO5B (60402-8-Ig) by Proteintech is a Monoclonal antibody targeting MYO5B in WB, ELISA applications with reactivity to human samples\n60402-8-Ig targets MYO5B in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: LNCaP cells, A431 cells,  HaCaT cells,  MCF-7 cells,  HepG2 cells,  LoVo cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nMYO5B is a member of the class V of unconventional, dimeric nonfilamentous myosins, which may be involved in vesicular trafficking.Members of the Rab family of small GTPases, consisting of Rab11a, Rab11b, and Rab25, have recently emerged as potential mediators of vesicle transport by MYO5B. MYO5B is required for polarization of hepatocytes and mutations of MYO5B\ncould disrupt epithelial cell polarity. Loss-of-Function of MYO5B caused by mutation is the main cause of microvillus inclusion disease (MVID). Recently it was reported that the expression of MYO5B was downregulated in gastric cancer and inactivation of MYO5B may contribute to tumorigenesis.(22134786)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Mouse \/ IgG2a\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag32670 Product name: Recombinant human MYO5B protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 940-1114 aa of NM_001080467 Sequence: EFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYP Predict reactive species\nFull Name: myosin VB\nCalculated Molecular Weight: 214KD\nObserved Molecular Weight: 200-220 kDa\nGenBank Accession Number: NM_001080467\nGene Symbol: MYO5B\nGene ID (NCBI): 4645\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q9ULV0\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888301428905,"sku":"60402-8-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-60402-8-ig","provider":"Iright","version":"1.0","type":"link"}