{"product_id":"proteintech-65052-1-ig","title":"Proteintech, 65052-1-Ig, Anti-Mouse CD107b \/ LAMP2 (ABL-93)","description":"Size: 100ug \/ 500ug\nThe CD107b \/ LAMP2 (65052-1-Ig) by Proteintech is a Monoclonal antibody targeting CD107b \/ LAMP2 in IF\/ICC, FC (Intra) applications with reactivity to mouse samples\n65052-1-Ig targets CD107b \/ LAMP2 in IF\/ICC, FC (Intra) applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: NIH\/3T3 cells\nPositive FC (Intra) detected in: NIH\/3T3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.5 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nLAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells (PMID: 12221139). LAMP is involved in lysosomal stability and autophagy (PMID: 12221139). This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis (PMID 9426697).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nCited Reactivity: mouse\nHost \/ Isotype: Rat \/ IgG2a, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Glycoproteins purified from BALB\/c mouse embryo 3T3 cell line Predict reactive species\nFull Name: lysosomal-associated membrane protein 2\nGenBank Accession Number: BC138718\nGene Symbol: CD107b \/ LAMP2\nGene ID (NCBI): 16784\nRRID: AB_2881468\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: P17047\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888054423721,"sku":"65052-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-65052-1-ig","provider":"Iright","version":"1.0","type":"link"}