{"product_id":"proteintech-65073-1-ig","title":"Proteintech, 65073-1-Ig, Anti-Mouse PD-L1\/CD274 (10F.9G2)","description":"Size: 500ug\nThe PD-L1\/CD274 (65073-1-Ig) by Proteintech is a Monoclonal antibody targeting PD-L1\/CD274 in FC applications with reactivity to mouse samples\n65073-1-Ig targets PD-L1\/CD274 in IHC, FC applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: Anti-CD3\/CD28 stimulated mouse splenocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nProgrammed cell death ligand 1 (PD-L1, CD274, or B7-H1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. PD-L1 is suggested as a negative regulator of T and B cell, and plays important role in mediating tolerance of lymphocytes to self-antigens. It is also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PD-1-independent manner.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nCited Reactivity: human\nHost \/ Isotype: Rat \/ IgG2b, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: N\/A Predict reactive species\nFull Name: CD274 antigen\nGenBank Accession Number: BC066841\nGene Symbol: PD-L1\nGene ID (NCBI): 60533\nRRID: AB_3670271\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: Q9EP73\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888055111849,"sku":"65073-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-65073-1-ig","provider":"Iright","version":"1.0","type":"link"}