{"product_id":"proteintech-65090-1-ig","title":"Proteintech, 65090-1-Ig, Anti-Human CD16 (3G8)","description":"Size: 100ug \/ 500ug\nThe CD16 (65090-1-Ig) by Proteintech is a Monoclonal antibody targeting CD16 in FC applications with reactivity to Human samples\n65090-1-Ig targets CD16 in FC applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B. Clone 3G8 recognizes both the CD16a and CD16b (PMID: 7592758).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: N\/A Predict reactive species\nFull Name: Fc fragment of IgG, low affinity IIIa, receptor (CD16a)\nCalculated Molecular Weight: 254 aa, 29 kDa\nGenBank Accession Number: BC017865\nGene Symbol: CD16a\nGene ID (NCBI): 2214\nENSEMBL Gene ID: ENSG00000203747\nRRID: AB_2918393\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: P08637\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888087879849,"sku":"65090-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-65090-1-ig","provider":"Iright","version":"1.0","type":"link"}