{"product_id":"proteintech-65116-1-ig","title":"Proteintech, 65116-1-Ig, Anti-Human CD11b (ICRF44)","description":"Size: 500ug\nThe CD11b (65116-1-Ig) by Proteintech is a Monoclonal antibody targeting CD11b in FC applications with reactivity to Human samples\n65116-1-Ig targets CD11b in FC applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIntegrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α\/β heterodimer with CD18 (integrin β2). CD11b\/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b\/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nCited Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Rheumatoid synovial cells and human monocytes Predict reactive species\nFull Name: integrin, alpha M (complement component 3 receptor 3 subunit)\nCalculated Molecular Weight: 1152 aa, 127 kDa\nGenBank Accession Number: BC096346\nGene Symbol: CD11b\nGene ID (NCBI): 3684\nENSEMBL Gene ID: ENSG00000169896\nRRID: AB_2918412\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: P11215\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888053833897,"sku":"65116-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-65116-1-ig","provider":"Iright","version":"1.0","type":"link"}