{"product_id":"proteintech-65117-1-ig","title":"Proteintech, 65117-1-Ig, Anti-Mouse CD44 (IM7)","description":"Size: 500ug\nThe CD44 (65117-1-Ig) by Proteintech is a Monoclonal antibody targeting CD44 in IF\/ICC, FC applications with reactivity to Human, Mouse samples\n65117-1-Ig targets CD44 in IHC, IF\/ICC, FC applications and shows reactivity with Human, Mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: HeLa cells\nPositive FC detected in: mouse splenocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:400\nFlow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, Mouse\nHost \/ Isotype: Rat \/ IgG2b, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Dexamethasone-induced myeloid leukemia M1 cells Predict reactive species\nFull Name: CD44 antigen\nGenBank Accession Number: BC051388\nGene Symbol: Cd44\nGene ID (NCBI): 12505\nRRID: AB_2918413\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P15379\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888054751401,"sku":"65117-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-65117-1-ig","provider":"Iright","version":"1.0","type":"link"}