{"product_id":"proteintech-65118-1-ig","title":"Proteintech, 65118-1-Ig, Anti-Human CD86 (IT2.2)","description":"Size: 100ug \/ 500ug\nThe CD86 (65118-1-Ig) by Proteintech is a Monoclonal antibody targeting CD86 in FC applications with reactivity to Human samples\n65118-1-Ig targets CD86 in FC applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. (PMID: 7513726; 1847722; 11029388; 27591335)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG2b, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: N\/A Predict reactive species\nFull Name: CD86 molecule\nCalculated Molecular Weight: 329 aa, 38 kDa\nGenBank Accession Number: BC040261\nGene Symbol: CD86\nGene ID (NCBI): 942\nENSEMBL Gene ID: ENSG00000114013\nRRID: AB_3084900\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P42081\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888094990505,"sku":"65118-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-65118-1-ig","provider":"Iright","version":"1.0","type":"link"}