{"product_id":"proteintech-65138-1-ig","title":"Proteintech, 65138-1-Ig, Anti-Mouse NK1.1 (CD161) (PK136)","description":"Size: 500ug\nThe NK1\n65138-1-Ig targets NK1.1 (CD161) in FC applications and shows reactivity with Mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: C57BL\/6 mouse splenocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nNK1.1 (CD161), also known as KLRB1 or NKR-P1A, is a type II transmembrane C-type lectin-like receptor and is expressed on the cell membrane as disulfide-linked homodimer (PMID: 8077657). It is expressed by the majority of NK cells and subsets of peripheral T cells, including both CD4+ and CD8+ T cells, and is expressed preferentially on adult T cells with a \"memory\" antigenic phenotype (PMID: 8077657; 22566826). Expression of CD161 correlates with the cytotoxic function of CD16+ NK cells, and ligation of CD161 with its ligand LLT1 inhibits NK cell cytotoxicity and cytokine secretion (PMID: 29686665).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Mouse\nHost \/ Isotype: Mouse \/ IgG2a, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: NK-1+ cells from mouse spleen and bone marrow Predict reactive species\nFull Name: killer cell lectin-like receptor subfamily B member 1A\nGenBank Accession Number: BC120707\nGene Symbol: NK1.1\nGene ID (NCBI): 17057\nRRID: AB_2918425\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: P27811\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888098365609,"sku":"65138-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-65138-1-ig","provider":"Iright","version":"1.0","type":"link"}