{"product_id":"proteintech-65154-1-ig","title":"Proteintech, 65154-1-Ig, Anti-Human CD117\/c-Kit (104D2)","description":"Size: 100ug\nThe CD117\/c-Kit (65154-1-Ig) by Proteintech is a Monoclonal antibody targeting CD117\/c-Kit in FC applications with reactivity to human, bovine samples\n65154-1-Ig targets CD117\/c-Kit in FC applications and shows reactivity with human, bovine samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: TF-1 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 1.5 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD117, also known as c-Kit and SCFR, is a transmembrane protein with tyrosine kinase activity encoded by the oncogene c-kit (PMID: 2448137). It is a member of the type III receptor tyrosine kinase family, which also includes CSF-1R, PDGFRβ, PDGFRα, and FLT3 (PMID: 29518044). CD117 is expressed on hematopoietic stem cells and progenitor cells, mast cells, and is also found in a wide range of non-haemopoietic cell types (including melanocytes, germ cells, astrocytes, renal tubules, breast glandular epithelial cells, sweat glands, and interstitial cells of Cajal) (PMID: 10582338; 23073628). CD117 plays an important role in early haemopoiesis. It is also involved in pigmentation, fertility, gut movement, and some aspects of the nervous system (PMID: 23073628).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, bovine\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: MOLM-1 megakaryocytic cells Predict reactive species\nFull Name: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog\nCalculated Molecular Weight: 976 aa, 110 kDa\nGenBank Accession Number: BC071593\nGene Symbol: CD117\nGene ID (NCBI): 3815\nRRID: AB_2918436\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Purified by protein-A affinity chromatography\nUNIPROT ID: P10721\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888871035049,"sku":"65154-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-65154-1-ig","provider":"Iright","version":"1.0","type":"link"}