{"product_id":"proteintech-65190-1-ig","title":"Proteintech, 65190-1-Ig, Anti-Human CD18 (TS1\/18)","description":"Size: 100ug \/ 500ug\nThe CD18 (65190-1-Ig) by Proteintech is a Monoclonal antibody targeting CD18 in FC applications with reactivity to human samples\n65190-1-Ig targets CD18 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a\/CD18 (LFA-1) is expressed by all leukocytes, while CD11b\/CD18 (Mac-1) and CD11c\/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Human Beta 2 Integrin Predict reactive species\nFull Name: integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)\nCalculated Molecular Weight: 85 kDa\nGenBank Accession Number: BC005861\nGene Symbol: CD18\nGene ID (NCBI): 3689\nENSEMBL Gene ID: ENSG00000160255\nRRID: AB_2918460\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P05107\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888053899433,"sku":"65190-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-65190-1-ig","provider":"Iright","version":"1.0","type":"link"}