{"product_id":"proteintech-65562-1-mr","title":"Proteintech, 65562-1-MR, Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody","description":"Size: 100ug\nThe CD19 (65562-1-MR) by Proteintech is a Recombinant antibody targeting CD19 in FC applications with reactivity to human samples\n65562-1-MR targets CD19 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Mouse \/ IgG2a\nClass: Recombinant\nType: Antibody\nImmunogen: Human chronic lymphocytic leukemia (CLL) cells Predict reactive species\nFull Name: CD19 molecule\nCalculated Molecular Weight: 556 aa, 61 kDa\nGenBank Accession Number: BC006338\nGene Symbol: CD19\nGene ID (NCBI): 930\nENSEMBL Gene ID: ENSG00000177455\nRRID: AB_3670316\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P15391\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888540700841,"sku":"65562-1-MR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-65562-1-mr","provider":"Iright","version":"1.0","type":"link"}