{"product_id":"proteintech-66913-1-ig","title":"Proteintech, 66913-1-Ig, CD155\/PVR Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe CD155\/PVR (66913-1-Ig) by Proteintech is a Monoclonal antibody targeting CD155\/PVR in WB, ELISA applications with reactivity to human samples\n66913-1-Ig targets CD155\/PVR in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: U2OS cells, K-562 cells,  HT-1080 cells,  U-251 cells,  A549 cells,  HT-29 cells,  HepG2 cells,  HeLa cells,  HEK-293 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD155, also known as PVR, is a type I transmembrane glycoprotein in the immunoglobulin superfamily. It contains three extracellular immunoglobulin-like domains, D1-D3, of which D1 is recognized by the virus. Mature human CD155 consists of a 323 amino acid extracellular domain with one N-terminal V-type and two C2-type Ig-like domains, a 24 amino acid transmembrane segment, and a 50 amino acid cytoplasmic tail. CD155 is thought to play a role in adhesion by interaction with the ECM component vitronectin as well as a role in NK killing of tumor cells. CD155 binds to two receptors of NK cells, CD96 and CD226, and accumulates at cell-cell contact sites, leading to the formation of mature immune synapses between NK cells and target cells. CD155 serves as the entry receptor for poliovirus and thereby mediates human susceptibility to poliovirus infection.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag28303 Product name: Recombinant human PVR protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 21-115 aa of BC015542 Sequence: WPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRV Predict reactive species\nFull Name: poliovirus receptor\nCalculated Molecular Weight: 45 kDa\nObserved Molecular Weight: 60-70 kDa\nGenBank Accession Number: BC015542\nGene Symbol: CD155\/PVR\nGene ID (NCBI): 5817\nRRID: AB_2882240\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: P15151\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888057897129,"sku":"66913-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-66913-1-ig","provider":"Iright","version":"1.0","type":"link"}