{"product_id":"proteintech-67537-1-ig","title":"Proteintech, 67537-1-Ig, KLRB1\/CD161 Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe KLRB1\/CD161 (67537-1-Ig) by Proteintech is a Monoclonal antibody targeting KLRB1\/CD161 in WB, ELISA applications with reactivity to human samples\n67537-1-Ig targets KLRB1\/CD161 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: human spleen tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD161, also known as KLRB1 or NKR-P1A, is a type II transmembrane C-type lectin-like receptor and is expressed on the cell membrane as disulfide-linked homodimer (PMID: 8077657). It is expressed by the majority of NK cells and subsets of peripheral T cells, including both CD4+ and CD8+ T cells, and is expressed preferentially on adult T cells with a \"memory\" antigenic phenotype (PMID: 8077657; 22566826). Expression of CD161 correlates with the cytotoxic function of CD16+ NK cells, and ligation of CD161 with its ligand LLT1 inhibits NK cell cytotoxicity and cytokine secretion (PMID: 29686665).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag27117 Product name: Recombinant human KLRB1,CD161 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 68-225 aa of BC114516 Sequence: KSSIEKCSVDIQQSRNKTTERPGLLNCPIYWQQLREKCLLFSHTVNPWNNSLADCSTKESSLLLIRDKDELIHTQNLIRDKAILFWIGLNFSLSEKNWKWINGSFLNSNDLEIRGDAKENSCISISQTSVYSEYCSTEIRWICQKELTPVRNKVYPDS Predict reactive species\nFull Name: killer cell lectin-like receptor subfamily B, member 1\nCalculated Molecular Weight: 225 aa, 25 kDa\nObserved Molecular Weight: 32 kDa\nGenBank Accession Number: BC114516\nGene Symbol: CD161\nGene ID (NCBI): 3820\nENSEMBL Gene ID: ENSG00000111796\nRRID: AB_2882756\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: Q12918\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888003829929,"sku":"67537-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-67537-1-ig","provider":"Iright","version":"1.0","type":"link"}