{"product_id":"proteintech-67649-1-ig","title":"Proteintech, 67649-1-Ig, GNE Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe GNE (67649-1-Ig) by Proteintech is a Monoclonal antibody targeting GNE in WB, ELISA applications with reactivity to Human, rat samples\n67649-1-Ig targets GNE in WB, ELISA applications and shows reactivity with Human, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, Hela cells,  HEK-293 cells,  Jurkat cells,  K-562 cells,  HSC-T6 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe bifunctional enzyme UDP-N-acetylglucosamine-2-epimerase\/N-acetylmannosamine kinase (GNE) is essential for early embryonic development and catalyzes the rate limiting step in sialic acid biosynthesis. It plays an important role in neuronal cell and brain development, and is strongly involved in cardiac tissue and skeletal muscle early survival and organization.. This protein has 5 isoforms produced by alternative splicing.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, rat\nCited Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag18702 Product name: Recombinant human GNE protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 376-722 aa of BC121179 Sequence: SIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY Predict reactive species\nFull Name: glucosamine (UDP-N-acetyl)-2-epimerase\/N-acetylmannosamine kinase\nCalculated Molecular Weight: 722 aa, 79 kDa\nObserved Molecular Weight: 79 kDa\nGenBank Accession Number: BC121179\nGene Symbol: GNE\nGene ID (NCBI): 10020\nRRID: AB_2882849\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: Q9Y223\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888042430633,"sku":"67649-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-67649-1-ig","provider":"Iright","version":"1.0","type":"link"}