{"product_id":"proteintech-68130-1-ig","title":"Proteintech, 68130-1-Ig, RYBP Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe RYBP (68130-1-Ig) by Proteintech is a Monoclonal antibody targeting RYBP in WB, ELISA applications with reactivity to Human, mouse samples\n68130-1-Ig targets RYBP in WB, ELISA applications and shows reactivity with Human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, RAW 264.7 cells,  HeLa cells,  U2OS cells,  HEK-293 cells,  LNCaP cells,  Jurkat cells,  Daudi cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPolycomb repressive complexes (PRCs) are important chromatin regulators of embryonic stem (ES) cell function [PMID:22269950]. RYBP binds Polycomb H2A monoubiquitin ligases Ring1A and Ring1B and has been suggested to assist PRC localization to their targets. RYBP, firstly identified as a direct interactor with Ring1A, acts as transcriptional repressor in reporter assays, both in tissue culture cells and in the fly [PMID:16125914]\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, mouse\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag31715 Product name: Recombinant human RYBP protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-228 aa of BC014959 Sequence: MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF Predict reactive species\nFull Name: RING1 and YY1 binding protein\nCalculated Molecular Weight: 228 aa, 25 kDa\nObserved Molecular Weight: 32 kDa\nGenBank Accession Number: BC014959\nGene Symbol: RYBP\nGene ID (NCBI): 23429\nRRID: AB_2923657\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: Q8N488\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888321024169,"sku":"68130-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-68130-1-ig","provider":"Iright","version":"1.0","type":"link"}