{"product_id":"proteintech-68135-1-ig","title":"Proteintech, 68135-1-Ig, IL-11 Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe IL-11 (68135-1-Ig) by Proteintech is a Monoclonal antibody targeting IL-11 in WB, ELISA applications with reactivity to human samples\n68135-1-Ig targets IL-11 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Saos-2 supernatant cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nInterleukin-11 (IL-11) is a member of the glycoprotein-130 (GP-130) cytokines that utilizes the GP-130 signaling pathway shared by other cytokines of the same family. The most well-known role of IL-11 is in\nhematopoiesis because it promotes megakaryocytopoiesis, erythropoiesis,\nand thrombopoiesis. In recognition of these properties, human IL-11 recombinant protein  (rhIL-11) is used clinically for treating chemotherapy-induced thrombocytopenia. IL-11 has extensive immunomodulatory effects, both anti- and proinflammatory.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Mouse \/ IgG2b\nClass: Monoclonal\nType: Antibody\nAffinity: K D =1.80 x 10 -9 M K Off =2.20 x 10 -6 M K On =1.22 x 10 3 M\nImmunogen: CatNo: Ag11199 Product name: Recombinant human IL-11 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-199 aa of BC012506 Sequence: MNCVCRLVLVVLSLWPDTAVAPGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLKTLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIRAALAILGGLHLTLDWAVRGLLLLKTRL Predict reactive species\nFull Name: interleukin 11\nCalculated Molecular Weight: 199 aa, 21 kDa\nObserved Molecular Weight: 21 kDa\nGenBank Accession Number: BC012506\nGene Symbol: IL-11\nGene ID (NCBI): 3589\nRRID: AB_2923662\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P20809\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888286060713,"sku":"68135-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-68135-1-ig","provider":"Iright","version":"1.0","type":"link"}