{"product_id":"proteintech-68538-1-ig","title":"Proteintech, 68538-1-Ig, 4-Hydroxynonenal Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe 4-Hydroxynonenal (68538-1-Ig) by Proteintech is a Monoclonal antibody targeting 4-Hydroxynonenal in ELISA applications with reactivity to 4-hydroxynonenal, chemical compound samples\n68538-1-Ig targets 4-Hydroxynonenal in WB, IHC, IF, ELISA applications and shows reactivity with 4-hydroxynonenal, chemical compound samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive ELISA detected in: 4-Hydroxynonenal\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nEnzyme-linked Immunosorbent Assay (ELISA): ELISA : 1:5000-1:20000\n\u003cb\u003eBackground Information\u003c\/b\u003e\n4-Hydroxynonenal is a uremic toxin. Uremic toxins can be subdivided into three major groups based upon their chemical and physical characteristics: 1) small, water-soluble, non-protein-bound compounds, such as urea; 2) small, lipid-soluble and\/or protein-bound compounds, such as the phenols and 3) larger so-called middle-molecules, such as beta2-microglobulin. 4-Hydroxynonenal (4-HNE) is a major aldehydic product of ω-6-unsaturated fatty acid peroxidation. It is considered a lipid peroxidation specific marker. 4-HNE has been found to induce differentiation and inhibit proliferation of HL-60 human leukemic cells. It has also been found to induce murine alveolar macrophage cell death. 4-HNE has been shown to inhibit State 3 respiration, causing a transient cytosolic Ca2+ increase. In addition, it irreversibly inhibits Na+-K+-ATPase activity.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: 4-hydroxynonenal, chemical compound\nCited Reactivity: mouse, rat\nHost \/ Isotype: Mouse \/ IgG2a\nClass: Monoclonal\nType: Antibody\nImmunogen: PTG Predict reactive species\nFull Name: 4-Hydroxynonenal\nRRID: AB_3085246\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888024277161,"sku":"68538-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-68538-1-ig","provider":"Iright","version":"1.0","type":"link"}