{"product_id":"proteintech-69520-1-ig","title":"Proteintech, 69520-1-Ig, NeutraControl PDGF-BB Monoclonal antibody","description":"Size: 100ug\nThe NeutraControl PDGF-BB (69520-1-Ig) by Proteintech is a Monoclonal antibody targeting NeutraControl PDGF-BB in ELISA, Non-Neutralization applications with reactivity to Human samples\n69520-1-Ig targets  PDGF-BB in ELISA, Non-Neutralization applications and shows reactivity with Human samples.\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPlatelet-derived growth factor (PDGF) belongs to the family of growth factors consisting of four secreted extracellular ligands including PDGF-A, -B, -C and -D. These isoforms, PDGF-AA, PDGF-AB, PDGF-BB, PDGF-CC and PDGF-DD, act via two receptor tyrosine kinases, PDGF receptors alpha and beta. PDGF isoforms stimulate growth, survival and motility of mesenchymal cells and certain other cell type. They have important functions during embryonal development and in the control of tissue homeostasis in the adult. PDGF-BB is one of the most recently studied isoforms and it plays an important role in skeletal development. PDGF-BB stimulates cell-mediated collagen gel contraction. PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.This antibody is a neutralizing control antibody for PDGF-BB,  the immunogen is the same as Neutrakine 69020-1-Ig but could not neutralize human PDGF-BB.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nCited Reactivity: human\nHost \/ Isotype: Mouse \/ IgG2a\nClass: Monoclonal\nType: Antibody\nImmunogen: RecombinantProtein Predict reactive species\nFull Name: platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)\nGene Symbol: PDGFB\nGene ID (NCBI): 5155\nRRID: AB_2918854\nConjugate: Unconjugated\nForm: Lyophilized Powder\nPurification Method: Protein A purification\nUNIPROT ID: P01127\nStorage Buffer: Sterile PBS, pH 7.4.\nEndotoxin: \u0026lt;0.1 EU\/μg\nReconstitution: This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg\/mL in sterile H2O before use.\nStability and Storage: Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888068841641,"sku":"69520-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-69520-1-ig","provider":"Iright","version":"1.0","type":"link"}