{"product_id":"proteintech-83223-4-rr","title":"Proteintech, 83223-4-RR, Nectin-4\/PVRL4 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Nectin-4\/PVRL4 (83223-4-RR) by Proteintech is a Recombinant antibody targeting Nectin-4\/PVRL4 in IF\/ICC, FC, ELISA applications with reactivity to human samples\n83223-4-RR targets Nectin-4\/PVRL4 in IF\/ICC, FC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: MCF-7 cells\nPositive FC detected in: MCF-7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nNectin-4, or PVRL4, belongs to the family of cell adhesion molecules that regulate the formation of adherence functions in epithelial cells through the AF-6 afadin scaffold molecule. Nectin-4 is reported as a histological and serological marker for breast carcinoma. Nectin-4 can be detected as a soluble form of 43 kDa and a transmembrane form of 66 kDa (PMID: 15784625).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nAffinity: K D =2.28 x 10 -10 M K Off =2.98 x 10 -5 M K On =2.62 x 10 5 M\nImmunogen: Recombinant protein Predict reactive species\nFull Name: poliovirus receptor-related 4\nCalculated Molecular Weight: 510 aa, 55 kDa\nGenBank Accession Number: BC010423\nGene Symbol: Nectin-4\nGene ID (NCBI): 81607\nRRID: AB_3670907\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q96NY8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888862449833,"sku":"83223-4-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-83223-4-rr","provider":"Iright","version":"1.0","type":"link"}