{"product_id":"proteintech-83683-6-rr","title":"Proteintech, 83683-6-RR, Beta-2-Microglobulin Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Beta-2-Microglobulin (83683-6-RR) by Proteintech is a Recombinant antibody targeting Beta-2-Microglobulin in WB, IHC, IP, ELISA applications with reactivity to human samples\n83683-6-RR targets Beta-2-Microglobulin in WB, IHC, IP, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A431 cells, HepG2 cells,  Raji cells,  U-937 cells,  Jurkat cells\nPositive IP detected in: A431 cells\nPositive IHC detected in: human tonsillitis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\nImmunohistochemistry (IHC): IHC : 1:400-1:1600\n\u003cb\u003eBackground Information\u003c\/b\u003e\nBeta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions due to shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag4433 Product name: Recombinant human B2M protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 22-119 aa of BC032589 Sequence: QRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM Predict reactive species\nFull Name: beta-2-microglobulin\nCalculated Molecular Weight: 119 aa, 14 kDa\nObserved Molecular Weight: 12 kDa\nGenBank Accession Number: BC032589\nGene Symbol: B2M\nGene ID (NCBI): 567\nENSEMBL Gene ID: ENSG00000166710\nRRID: AB_3671284\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P61769\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888396193961,"sku":"83683-6-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-83683-6-rr","provider":"Iright","version":"1.0","type":"link"}