{"product_id":"proteintech-84563-1-rr","title":"Proteintech, 84563-1-RR, Phospho-SH3PXD2B (Ser291) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-SH3PXD2B (Ser291) (84563-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-SH3PXD2B (Ser291) in WB, IF\/ICC, ELISA applications with reactivity to human samples\n84563-1-RR targets Phospho-SH3PXD2B (Ser291) in WB, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, λ phosphatase treated HeLa cells\nPositive IF\/ICC detected in: λ phosphatase treated HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSH3 and PX domains 2B (SH3PXD2B) is also known as tyrosine kinase substrate with four SH3 domains (Tks4). It consists of the N-terminal phox homology domain, four Sr homology 3 domains, several proline-rich regions, and Src phosphorylation sites. Previous studies have shown that SH3PXD2B is an essential invadopodium scaffold protein and can stimulate actin polymerization, recruit membrane type-1 matrix metalloproteinase (MT1-MMP) to intracellular membranes, and increase Nox1-dependent reactive oxygen species (ROS) production. (PMID: 33906640)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: SH3 and PX domains 2B\nCalculated Molecular Weight: 911aa, 102 kDa\nObserved Molecular Weight: 120 kDa\nGenBank Accession Number: NM_001017995\nGene Symbol: SH3PXD2B\nGene ID (NCBI): 285590\nRRID: AB_3672071\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: A1X283\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888804384937,"sku":"84563-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-84563-1-rr","provider":"Iright","version":"1.0","type":"link"}